Natural Products from Local Medicinal Plants for Pest Management

Natural Products from Local Medicinal Plants for Pest Management

Nakhonsawan Campus Mahidol University

Project Title:

Natural Products from Local Medicinal Plants for Pest Management

Research Title:

Natural Products from Local Medicinal Plants for Pest Management

Researcher (s):

Asst. Prof.Saksit Nobsathian, PhD and Bioinsecticide Research Group

This research, is focused on isolated bioactive compounds from local medicinal plants at Mahidol University Nakhonsawan Campus. Thailand is an agricultural country. There are many agricultural products which are exported. However, many outbreaks of insect pests have also been reported. The research team is interested in Spodoptera sp. insect outbreaks, beet armyworm (Spodoptera exigua Hübner), tobacco cutworm (Spodoptera litura) and fall armyworm (Spodoptera frugiperda), which have been reported in Nakhon Sawan Province.

These insects cause damage to plantation agriculture by feeding on crops. In this research, isolation of chemicals from the local medicinal plants in Nakhon Sawan Province has been conducted, for example, Maerua siamensis and Combretum tetralophum Clake.

Plant samples were purified, and then tested by antifeedant assay and topical application method. Acute mortality (LD₅₀, Median lethal dose) was also analyzed. Furthermore, mortality rate analysis being used to test the toxin destruction enzyme system and enzymes that affect the nervous system have been evaluated the pesticide resistance.

Publication:
• Nobsathian S, Bullangpoti V, Kumrungsee N, Wongsa N, Ruttanakum D. Larvicidal effect of compounds isolated from Maerua siamensis (Capparidaceae) against Aedes aegypti (Diptera: Culicidae) larvae. Chem Biol Tech Agirc 2018;5(8):1–7.
• Wiwattanawanichakun P, Poonsri W, Yooboon T, Piyasaengthong N, Bullangpoti V, Ratwatthananon A, Pluempanupat W, and Nobsathian S. The Possibility of Using Isolated Alkaloid Compounds and Crude Extracts of Piper retrofractum (Piperaceae) as Larvicidal Control Agents for Culex quinquefasciatus (Diptera: Culicidae) Larvae. J med entomol. 2018; 55(5), 1231-1236.

Key Contact Person:
Nakhonsawan Campus Mahidol University
402/1 Moo 5 Khaothong Phrayuhakiri District
Nakhonsawan Province 60130
+668 6445 6406, +669 9740 8132
saksit.nob@mahidol.ac.th